Lactobacillus gasseri | 5 Important Points

Lactobacillus gasseri

Lactobacillus gasseri

Lactobacillus gasseri is an acidophilic bacteria found naturally in the intestine. It has a variety of health benefits. It is also known for being effective at treating a variety of infections. Read on to learn more about its characteristics, health benefits, and uses. In addition, you can learn about its safety and precautions. You can also use Lactobacillus gasseri in your daily routine.


One study investigated the efficacy of Lactobacillus gasseri in the treatment of influenza A virus infection. Oral administration of this probiotic lactic acid bacterium improved survival rates and decreased virus titers in the lungs of mice. Flu virus infections are associated with massive infiltration of inflammatory cells and excessive production of proinflammatory cytokines. The researchers measured the number of inflammatory cells in BAL fluid and the number of IL-6 in lung homogenates.

In rats, L. gasseri increased energy expenditure, decreased BMI, and improved glucose tolerance. They also significantly reduced abdominal visceral fat and body weight in obese mice and rats. Additionally, L. gasseri reduced inflammation and insulin levels in mice and rats. These effects may require consistent consumption of Lactobacillus gasseri to maintain their effects. Additional research should be completed to assure the effectiveness of this probiotic.

The results of this study indicate that L. gasseri may inhibit the formation of gastric ulcers in rats. However, further studies are needed to determine if this bacterium affects host immune cells. However, the promising results point to the potential benefits of L. gasseri in treating intestinal infections and allergies. And if the findings of this study are confirmed in humans, this probiotic may be useful for treating oxalate kidney stones in humans.

While consuming a high-quality probiotic supplement may help prevent gas and bloating, it is not always sufficient. No clinical trials prove that this strain is superior to other probiotics. Furthermore, it may cause side effects such as diarrhea or gas. Thus, the use of Lactobacillus in daily supplementation may not be recommended. If you are taking antibiotics for a medical condition, you should consult with a doctor before starting a probiotic supplement.


To study the potential role of Lactobacillus gasseri as a probiotic, researchers conducted experiments in mice. They administered the probiotics in sterile PBS to C57BL/6J mice and collected fecal pellets before, during, and after the probiotics were given. Fecal pellets were homogenized in 1 ml of sterile PBS and plated onto MRS agar containing 2 mg/ml erythromycin. The amount of erythromycin in mouse feces was used to calculate the CFU of each strain.

In addition to enhancing the probiotic activity of L. gasseri, elevated levels of MnSOD have increased the survival of L. gasseri cultures in vitro. Oxidative stress is common in the mammalian gut, especially in inflamed tissues, and elevated levels of MnSOD may counteract this oxidative insult. Increased MnSOD may also allow engineered L. gasseri to establish more intimate contact with colon epithelium.

Using 16S rDNA sequences, researchers identified 92 strains of L. gasseri. They then performed whole-genome analyses and compared their ANI values. This analysis revealed the presence of two new species in the genus, L. paragasseri K7, and L. gasseri ATCC33323. The new species has an open pan-genome and super genome that is 3.3 times larger than the average genome size.

One of the most striking features of Lactobacillus gasseri is its ability to convert into a plasmid with heterologous genes. Moreover, the bacteria have a genome sequence for one temperate bacteriophage. These characteristics have led to the development of genetic tools and functional genomic analysis of Lactobacillus gasseri. The potential for Lactobacillus gasseri to improve the health and wellness of human beings is endless.

Health benefits

There are several lactobacillus gasseri health-related supplements available today. You can purchase them at many health food stores, grocery stores, and drugstores. Although less popular in the United States, lactobacillus vaginal capsules and suppositories are available online. Depending on your circumstances, you may need to consult a physician before taking a probiotic supplement.

In a study published in the British Journal Of Nutrition, researchers used 210 healthy Japanese volunteers to test Lactobacillus gasseri and its health benefits. They took SBT2055, a strain of Lactobacillus, in liquid milk for 12 weeks. The placebo party did not encounter any meaningful changes in their baseline measurements. For this reason, Lactobacillus gasseri may help overweight adults lose weight.

CP2305 has shown that lactobacillus gasseri may help with stress-related symptoms. This is likely because it colonizes the intestines and improves their environment. The heat-inactivated cells may stimulate the afferent vagal nerve and alter the activity of the HPA axis. Further, the lactobacillus-containing tablet may be useful for people suffering from stress-related symptoms.

Research on Lactobacillus rhamnosus health benefits in newborns has shown promising results. This strain of Lactobacillus may reduce the duration of daily crying in nursing infants. It may also be helpful for infants with irritable bowel syndrome or colic. Additionally, the benefits are beneficial in improving post-bowel surgery and preventing necrotizing enterocolitis.

The probiotic has been shown to reduce blood cholesterol levels, reducing LDL cholesterol levels in rats with metabolic syndrome. The bacterium also enhanced oral tolerance to cedar pollen antigen. In another study, heat-killed L. gasseri improved immune function in mice with rotavirus infection. Lastly, the bacteria also improved menstrual pain in mice. If this probiotic is beneficial for treating kidney stones, it may be an excellent choice as a health supplement.


While taking Lactobacillus Gasseri is generally safe, a few precautions should be taken before and after using this probiotic. It is important to remember that this product may cause side effects, although the list of possible side effects isn’t comprehensive. Some side effects may not occur at all, while others are rare. If you experience these side effects, consult your doctor or local food and drug administration authority.

You should also avoid ingesting this bacteria if you are immunosuppressed. Many people have had positive results after taking lactobacillus-containing products, including yogurt. However, this bacterial organism has been implicated in the development of dental caries and is, therefore, a concern for those who have had a dental procedure recently. Although these precautions are not recommended for everyone, they should be followed to ensure that you are not infected with them.

Another precaution is to take the correct dosage of Lactobacillus Gasseri/Lactobacillus rhamnosus. Excessive intake of this probiotic may cause serious side effects and result in poisoning. If you suspect an overdose, seek medical attention immediately. Bring the product’s box and label along to your appointment. Do not share or give the medicine to anyone, even if you are sure they haven’t taken it.

While Lactobacillus acidophilus is widely available in supplements, you should always check with your healthcare provider before taking this probiotic. It is necessary to determine that health accessories can also be sold for other purposes. Always follow the label to ensure that you are not taking harmful chemicals. And never take Lactobacillus acidophilus if you are pregnant, have low-quality milk, or have a weakened immune system.

Lactobacillus Probiotic | 2 Important Points

Lactobacillus gasseri

Interactions with other microorganisms

Studies have shown that Lactobacillus gasseri can improve glucose metabolism and may help alleviate some common ailments. Although few clinical trials involved humans, mice were treated with various Lactobacillus species, and metabolic changes were observed. In addition, studies in mice have revealed that some species share critical mechanisms of interaction with their mammalian host. To better understand how Lactobacillus gasseri can affect our health, we should understand how it interacts with other organisms.

A multi-omic network was developed to identify the mechanisms of Lactobacilli alteration of metabolism. It integrated gene expression data, lipid profiles from the liver, and systemic metabolic parameters that WD changed. The network spanned 1776 edges and 380 nodes, and it followed a power-law function. Enrichment analysis of the network revealed the presence of genes related to mitochondrial translation and autophagy formation.

The human skin microbiota serves as a protective barrier against skin pathogens and modulates the immune response. Studies have identified Lactobacilli as the endogenous inhabitants of healthy skin. Because disturbed microbiome composition is associated with inflammatory skin conditions, probiotics based on lactobacilli have been explored as a topical treatment for inflammatory skin.

Some studies involving Lactobacillus gasseri suggest that it may help control hyperuricemia. Moreover, a drinkable yogurt containing L. gasseri OLL2716 has been found to reduce the risk of infection and alleviate hyperuricemia. The effects of Lactobacillus gasseri may extend to other conditions, including inflammatory bowel disease, diabetes, and heart failure.

Lactobacillus gasseri | 5 Important Points

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