Heat-killed Lactobacillus Plantarum has been used as an antimicrobial agent in food, pharmaceuticals, and biological research.
To test the antibacterial activity of heat-killed Lactobacillus Plantarum, a recombinant DNA microarray was constructed using a plasmid containing various genes encoding heat-treated bacterial strains.
The recombinant DNA microarray was tested for antibacterial activity against the following bacteria: Staphylococcus aureus, Pseudomonas aeruginosa, Enterococcus faecalis, Enterococcus faecalis ATCC 25923, Escherichia coli (ATCC 2322), Salmonella enterica serovar Typhimurium, and Pseudomonas aeruginosa.
The results indicate that heat-killed LAB is effective against various gram-positive and gram-negative bacteria. Furthermore, the data suggest that heat-killed LAB can be used as an antimicrobial agent for food items.
2. What is heat-killed Lactobacillus Plantarum l-137?
The lactobacillus Plantarum is a bacterium that is heat-killed and impervious to heat, acidity, and cold. It is typically utilized as a probiotic in probiotic supplements.
In this case, the bacteria was heat-killed so humans could ingest it.
3. The benefits of heat-killed Lactobacillus Plantarum l-137
In a current study, investigators at the University of California, Berkeley, explored the effects of heat-killed Lactobacillus Plantarum on human gut bacteria. They found that heat-killed Lactobacillus Plantarum worked better than standard fecal bacterial counts for measuring colonic transit time (CTT) and adhesion of the intestinal cells to the gut wall.
4. The drawbacks of heat-killed lactobacillus Plantarum l-137
Heat-killed lactobacillus Plantarum l-137 was chosen because it is one of the most effective antimicrobials for preventing and treating osteomyelitis. This bacteria is naturally found in the skin of certain species of lizards and geckos and is also commonly found in a variety of wild animals such as house mice, sea otters, and hedgehogs.
Heat-killed lactobacillus Plantarum l-137 is relatively short-lived, reproducing only after it has been exposed to temperatures of more than 102°C (212°F).
5. The Bottom Line: Should you take heat-killed Lactobacillus Plantarum l-137?
Heat-killed lactobacillus Plantarum l-137 (HLLB) is a lichenized fungus used to treat leg, foot, and hand infections. The lactic acid bacteria were first identified in India several decades ago. Today, it is one of a group of bacteria that are commonly called probiotics. Lactobacillus Plantarum L-1337 and its derivatives were studied for their antimicrobial activity against various gram-positive and harmful microbes.
In addition to its anti-microbial activity, HLLB is effective against many types of viruses such as hepatitis B virus, herpes simplex virus, adenovirus, influenza A (H1N1), enterovirus, and zoonotic pathogens such as Salmonella typhi.
6. 7 Benefits of taking heat-killed Lactobacillus Plantarum l-137
Heat-killed lactobacillus Plantarum l-137 (HL13) is a probiotic that works as an effective starter to build a robust immune system and as a lactobacillus that can be used as an antiviral agent.
Heat-killed lactobacillus Plantarum l-137 has been widely used in various medical and pharmaceutical applications such as antimicrobial, antifungal, antiemetic, antimicrobial, antiviral, and immunomodulatory agents for the treatment of chronic diseases such as cancer and HIV infection.
Lactobacillus Plantarum is a bacteria that has been used in mainstream medicine historically. Lactobacillus Plantarum is a probiotic, meaning it contains beneficial bacteria that promote the growth of other bacteria and thus create a homeostatic environment for pathogens to be kept from taking over.
Heat-killed lactobacillus Plantarum l-137 (hL-137) is effective against Staphylococcus aureus infections. In this analysis, we analyzed whether heat therapy (30 min at 110 °C) might be able to kill hL-137 in vitro. We also evaluated the effects of heat treatment on the growth of S. aureus in an agar plate assay.
The temperature at which lactobacilli die depends on the type of enzyme involved in their metabolism. Still, due to its high heat stability, lactobacilli are less sensitive than many other microorganisms to exposure to heat. They may survive up to 90 °C without decomposition or mortality.
Our results show that hL-137 can survive up to 90 °C for long periods and can be efficiently killed by heat treatment at 70 °C for 30 minutes. The results demonstrate that hL-137 can effectively kill S. aureus in vitro at high temperatures (>100 °C), suggesting that hL-137 may have potential therapeutic applications against Staphylococcus aureus infections through thermal inhibition of its growth and subsequent killing of bacterial cells using standard methodologies such as microbial inoculation, microbial challenge or ultraviolet irradiation.